Risk Parity, Smart Beta, and McDonald’s McNuggets.
As people age, the blood-brain barrier deteriorates and becomes leaky, allowing infections to get into the brain. The brain responds by trapping the offending microbes in protein cages (made up of beta amyloid proteins). The leftover plaque is a hallmark of Alzherimer’s
The plaque is not cleared out efficiently by the brain and causes a pathway (involving tangled tau proteins) that cause the brain to become inflamed and killing many nerve cells.
A small subset of the population have a gene (ApoE2) that are good for sweeping out plaque. These people have a low risk for late-onset Alzheimers.
Yes, that’s what I’ve been sayin’, yo! This makes so much sense. Quote:
Have we corrected through time, rather than through price, enough to spark the next leg higher for the bull?
Calling a generational, secular bull rally starting within the next 18 months. 🎶 Good times are here to stay 🎶.
Are you talkin’ to me? Well, I’m the only one here.–Travis Bickle in “Taxi Driver”
It is the last line, “Well, I’m the only one here,” that never gets quoted. It is the truest line in the film. Travis Bickle exists in “Taxi Driver” as a character with a desperate need to make some kind of contact somehow–to share or mimic the effortless social interaction he sees all around him, but does not participate in.
The film can be seen as a series of his failed attempts to connect, every one of them hopelessly wrong…. He is so lonely that when he asks, “Who you talkin’ to?” he is addressing himself in a mirror.
This utter aloneness is at the center of “Taxi Driver,” one of the best and most powerful of all films
-Roger Ebert, film critic.
I read this piece in his essay a decade ago and it still stays with me. Ebert makes a great point that the classically quoted tough-guy speech is actually turned 180 when you consider the next sentence “Well I’m the only one here.” Behind many macho exteriors is vulnerability.
I was reminded of this today when reading about the hoopla over Draymond Green’s quote:
“Do I think [the Portland Trailblazers] are done? Of course I think they’re done.”
Media personalities called him arrogant, classless, disrespectful. There are still games left to be played.
What the media doesn’t quote is the next line he immediately says, “If I don’t think they’re done, I don’t know who else is going to think it.”
He’s saying if I can’t be the one to express confidence in and for my team, who else is going to play that role. Green shows a glimpse into the tough load he has to carry as the emotional center of his team. If he can’t be the one to tell his teammates that they are the best team in the world, are they going to believe it themselves?
Bill James, father of Sabermetrics, predicts in 2001 that the right set of conditions could lead to Donald Trump winning the presidency. No exaggeration. Amazing.
The markets have gotten more efficient and the alpha is gone. Active funds are having a tougher time making money. Why? Increased competition, stricter regulation (insider trading crack-downs), and the internet democratizing information.
Nice quote about mom and pop “main street” investors:
[Main street investors] have decided to take their ball and go home… and by ball, I mean capital, and by home, I mean low-cost index funds.